675+ Appendix Pick Up Lines And Rizz 2025-2026 ❤️✨

When it comes to funny, creative, and unique pick-up lines, nothing beats the quirky world of Appendix Pick Up Lines. Just like the appendix itself—often overlooked but surprisingly important—these lines can add humor, charm, and unexpected wit to your conversations. Whether you’re trying to impress your crush, break the ice, or simply get a laugh, these lines bring together humor, flirtation, and smooth rizz energy.

Over the years, I’ve experimented with countless flirty openers, and I can confidently say that the right pick-up line can completely change the mood of a conversation. In this blog, you’ll discover over 675 appendix pick-up lines—from cute and cheesy to clever and bold—that can help you stand out.

So, if you’ve ever wanted to add a little twist of humor and charm while staying effortlessly smooth, these lines are perfect for you. Let’s dive into the best appendix-inspired rizz lines for 2025-2026.

Table of Contents

1. Funny Appendix Pick Up Lines 😂

“Are you my appendix? Because I don’t need you, but life feels incomplete without you. ❤️”
“Just like an appendix, you make my heart swell unexpectedly. 💘”
“You’re like an appendix—mysterious, hard to explain, but impossible to ignore. 😉”
“If you were my appendix, I’d never want you removed. 💕”
“I must have appendicitis, because my stomach flips every time I see you. 😍”
“You’re like my appendix—suddenly painful when you’re not around. 💔”
“Forget surgery, you’re the only thing I need in my gut. 🥰”
“You make me feel all kinds of appendix-level complications. 😏”
“Are you inflammation? Because you light me up inside. 🔥”
“My appendix isn’t useless, it led me to you. 💖”
“You’re like an appendix—you make things complicated but worth it. 😘”
“Call me a surgeon, because I can’t take my eyes off your appendix beauty. 😎”
“Appendix or not, you’re the missing piece in my body. 💞”
“Is it hot in here, or is it just my appendix acting up for you? 🥵”
“You’re like appendix pain—sharp, sudden, and unforgettable. 💓”
“My appendix may be small, but my love for you is huge. 💌”
“I’d never let anyone cut you out of my life. 🫶”
“You make my appendix jealous—you’re more important. 🌟”
“I don’t need medical attention, I just need your attention. 💋”
“You’re like appendicitis—unexpected, but life-changing. 🤭”
“If love is surgery, then I’m ready for you. 🩺”
“Your smile inflames me more than my appendix ever could. 😍”
“You’re the appendix to my heart—small, but vital. 💗”
“Call me a hospital, because I’m here for your appendix emergency. 🏥”
“You may be an appendix, but you’re essential to my story. 📖”

2. Cute Appendix Pick Up Lines 🥰

“You’re like my appendix—tiny but stealing all my attention. 💕”
“Every time you smile, my appendix flutters. 🌸”
“If my appendix is useless, then why does it ache when you’re away? 🥹”
“Just like my appendix, you complete me in ways I can’t explain. 💖”
“You make my heart swell more than any appendix ever could. 💘”
“If love is inflammation, then you’ve set my appendix on fire. 🔥”
“I’d rather keep you than any vital organ. 🥰”
“You’re sweeter than appendix-free recovery ice cream. 🍦”
“You’re my appendix—mysterious, but I’d never let you go. 🌟”
“Even my appendix would agree you’re one in a million. 💎”
“You heal my soul better than any surgeon can fix my appendix. 🩺”
“When you’re around, I don’t feel appendix pain—only butterflies. 🦋”
“You’re my appendix—small, rare, and absolutely priceless. 💝”
“I’d never remove you, even if you were trouble. 😍”
“You make my appendix feel jealous—you’re more special. 💫”
“Without you, I’d feel like an appendix with no purpose. 😌”
“You make my appendix pain feel like love pain. 🥲”
“You’re like my appendix—unexpected but perfect. 🌹”
“If you were my appendix, I’d protect you forever. 🛡️”
“You light up my life like appendix symptoms light up a scan. ✨”
“You’re the appendix of my heart—tiny, but powerful. ❤️”
“Even surgery couldn’t take you out of my thoughts. 🩹”
“You make my appendix ache in the best way. 🥵”
“My appendix may be small, but my love for you is endless. 🌊”
“With you, even appendix pain would be worth it. 💌”

3. Cheesy Appendix Pick Up Lines 🧀

“Are you my appendix? Because I can’t function without you. 😘”
“You’re so hot, you’re giving me appendix fever. 🔥”
“I’d let you operate on my heart any day. 🩺”
“I don’t need a scan to know you’re the one. 🖤”
“You must be my appendix—because I’d cross oceans for you. 🌊”
“I’m burning up inside, and it’s not appendicitis—it’s love. ❤️‍🔥”
“You’re like an appendix—you may seem small, but you’re unforgettable. 🌟”
“No doctor could remove the love I feel for you. 💘”
“Are you a CT scan? Because you make my heart visible. 📸”
“You’ve inflamed my appendix and my feelings. 😉”
“Even if you were useless, I’d still need you. 💕”
“Love hits me like appendix pain—sudden and sharp. 💥”
“You’re the appendix I’d never let go of. 🫶”
“You must be anesthesia—because you make me feel weightless. 😍”
“I’d happily wait in the ER just to see you. ⏳”
“If love were surgery, you’d be the best operation ever. 🏥”
“You’re so rare, even my appendix would bow to you. 👑”
“Forget the appendix, you’re the true mystery of life. 🌌”
“I must be under the knife, because you’ve stolen my heart. 💉”
“You’re like an appendix—hard to explain, impossible to live without. 💗”
“I’d take appendix pain daily just to be near you. 💞”
“Your love cuts deeper than any surgeon’s blade. ✂️”
“Even antibiotics can’t cure my love for you. 💊”
“You’re the only inflammation I never want cured. 😏”
“You make me blush harder than appendix surgery lights. 💡”

4. Clever Appendix Pick Up Lines 🧠

“If love were the appendix, you’d be the mystery scientists never solved. 🧩”
“Are you inflammation? Because you set my heart on fire. 🔥”
“They call the appendix useless, but you’ve proven otherwise. 😉”
“If appendix removal is common, loving you should be mandatory. 💘”
“You’re like my appendix—unexpected but unforgettable. 🥰”
“The appendix may have no purpose, but mine is loving you. ❤️”
“If I had appendicitis, you’d be my only cure. 🩺”
“You inflame my appendix like passion inflames my soul. 💓”
“Are you appendix pain? Because I can’t stop thinking about you. 🤯”
“Love is like an appendix—strange, complicated, but essential. 💕”
“You’re rarer than a healthy appendix. 🌟”
“They may remove the appendix, but never my love for you. 💘”
“If my appendix flares up, it’s just love for you. 🥹”
“You’re my appendix—misunderstood, but priceless. 🌸”
“Doctors can remove my appendix, but not my feelings. 🩹”
“If my appendix had a purpose, it would be to find you. 🧭”
“Are you appendix surgery? Because you cut straight to my heart. ✨”
“You’re the appendix to my soul—hard to explain but vital. 💞”
“Even science can’t explain why I love you. 🔬”
“You’re my appendix—people may not understand, but I do. 🥰”
“If appendix pain is sharp, your love is sharper. 💘”
“Forget evolution—you’re the reason I’m here. 🌍”
“You make me glow brighter than an appendix under X-ray. 💡”
“Love is like an appendix—rarely logical, always real. 💖”
“If appendicitis hurts, loving you heals. 💋”

5. Romantic Appendix Pick Up Lines ❤️

“You’re the appendix to my heart—small, but powerful in love. 💘”
“Even if the world removed me, I’d keep you forever. 🌍”
“You complete me in ways no surgeon could ever understand. 💕”
“My appendix may not matter, but you’re my everything. ❤️”
“I’d endure appendix pain just to see your smile. 😊”
“You’re the reason my heart beats faster than appendix flares. 💓”
“If love is surgery, I’ll always choose you as my cure. 🩺”
“You’re the appendix in my love story—unexpected but essential. 📖”
“Even anesthesia couldn’t put my love for you to sleep. 😍”
“Your love heals sharper than any scalpel. ✂️”
“You’re the only one I’d go under the knife for. 💌”
“When you hold me, appendix pain feels like a blessing. 🙏”
“You’re the appendix I never want removed. 🌹”
“I’d face surgery every day if it meant loving you. 💕”
“Your kiss is stronger than any painkiller. 💋”
“You’re my appendix—misunderstood, yet deeply loved. 💞”
“If you were my appendix, I’d guard you with my life. 🛡️”
“Love hits harder than appendix pain, and I’m glad it’s you. 💓”
“Your smile is brighter than a hospital light. 💡”
“I’d give up every organ, but never you. 🫀”
“You inflame my appendix with passion and love. 🔥”
“Even evolution couldn’t remove the love I feel for you. 🌟”
“You’re the cure to my lonely nights. 🌙”
“My appendix aches, but my love grows stronger. 💖”
“You’re the happily-ever-after to my appendix story. ✨”

6. Flirty Appendix Pick Up Lines 😉

“Are you my appendix? Because you’ve got me feeling hot and bothered. 🔥”
“You must be surgery, because you cut me deep—in a good way. ✂️”
“Your love inflames me more than appendicitis ever could. 😘”
“If you were my appendix, I’d keep you close all night. 🌙”
“Your touch is more addictive than painkillers. 💊”
“You set off alarms in my heart like appendix pain. 🚨”
“You’re the appendix I’d love to play doctor with. 🩺”
“Even anesthesia can’t knock me out when you’re around. 😏”
“You inflame more than my appendix, baby. 🔥”
“You’re sharper than appendix pain and twice as unforgettable. 💘”
“Are you a surgeon? Because you just cut into my heart. 💕”
“Your smile is my favorite kind of medicine. 💊”
“You’re so fine, even my appendix stands at attention. 😉”
“I’d let you operate on me anytime. 😎”
“You’ve got me sweating more than appendix fever. 🥵”
“You’re the appendix I’d never risk losing. 💋”
“You’re hotter than a hospital ER. 🔥”
“Even stitches couldn’t hold me back from you. 🪡”
“You’re the spark that sets off my appendix fire. 🔥”
“You’re more dangerous than appendix rupture—because I’m hooked. 😍”
“You’ve got me more twisted than an inflamed appendix. 💓”
“Your love is my emergency surgery. 🚑”
“You’re hotter than sterilized tools. 🛠️”
“My appendix isn’t useless—it brought me to you. 💞”
“Baby, you’re my diagnosis: dangerously attractive. 🩺”

7. Bold Appendix Pick Up Lines 🔥

“Forget anesthesia, I want to feel everything with you. 💘”
“You’re hotter than appendix inflammation at midnight. 🌙”
“I’d let you cut me open, just to see your smile. ✂️”
“You’re the appendix rupture of my heart—explosive and unstoppable. 💥”
“You turn pain into passion. 🔥”
“My appendix isn’t the only thing burning—it’s my desire for you. 😏”
“You’ve got me aching more than a surgeon’s patient. 🩺”
“I’d risk infection if it meant being close to you. 😘”
“You’re sharper than a scalpel and just as dangerous. 🔪”
“Appendix pain has nothing on the ache you give me. 💕”
“You’ve got me trembling more than appendix chills. ❄️”
“You’re like surgery—painful, but worth it. 🏥”
“You inflame my body in all the right ways. 🔥”
“You’re more intoxicating than morphine. 💊”
“Even appendix rupture isn’t as dramatic as falling for you. 💔”
“You’re the appendix explosion I can’t recover from. 💓”
“You slice through my defenses like a scalpel. ✂️”
“You’re hotter than a sterilizer flame. 🔥”
“Your love is my emergency room. 🚑”
“You’re the complication I’d risk my life for. 💕”
“You make me shiver like appendix fever. 🥶”
“My appendix is inflamed, but my heart is burning hotter. 💘”
“You’re the appendix I’d let rupture for love. 💥”
“You’re dangerous, beautiful, and exactly my type. 😎”
“No surgery could ever remove you from my soul. ❤️‍🔥”

8. Medical-Themed Appendix Pick Up Lines 🩺

“Are you a surgeon? Because you’ve just cut into my heart. 💉”
“You’re the only prescription I’ll ever need. 💊”
“You inflame my appendix like bacteria inflame the gut. 🔬”
“You’ve got me waiting in your ER of love. 🚑”
“Your smile is my ultimate diagnosis. 😍”
“Are you anesthesia? Because you make my worries disappear. 🌙”
“You’ve given me a love infection, and I don’t want a cure. 💕”
“You’re the appendix in my CT scan of life. 📸”
“You’ve raised my heart rate like a patient under stress. ❤️‍🔥”
“You’re the scalpel that opened my heart. ✂️”
“Forget antibiotics, your kiss is all I need. 💋”
“You’re the appendix pain that feels too good to treat. 😉”
“You’ve got me on oxygen just by being near. 🫁”
“You’re the MRI of my soul—showing my true feelings. 🧠”
“Your love inflames me worse than appendix swelling. 🔥”
“You’re the emergency call my heart’s been waiting for. 📞”
“Even surgery lights couldn’t shine brighter than you. 💡”
“You’re the vital sign my body craves. 🫀”
“You’re sharper than any scalpel in the OR. 🔪”
“Your touch is more healing than IV drips. 💦”
“You’re the appendix mystery no doctor could solve. 🧩”
“Your love feels like recovery after surgery—pure relief. 😌”
“I’d let you stitch my heart together. 🪡”
“Your smile hits harder than morphine. 💊”
“You’re my permanent prescription for happiness. 💝”

9. Nerdy Appendix Pick Up Lines 🤓

“Are you my appendix? Because science can’t explain why I need you. 🔬”
“You’re the hypothesis I’d test forever. 🧪”
“You’re rarer than a functional appendix. 🌟”
“Evolution may have left the appendix behind, but I’ll never leave you. 🐒”
“You’re the variable in my love equation. ➕”
“If love is biology, then you’re my appendix organelle. 🧬”
“You’re like appendix pain—hard to ignore. 🤓”
“You’re hotter than a lab burner. 🔥”
“You’ve got me running tests, but the results always say: love. ❤️”
“Are you DNA? Because you’re essential to my life. 🧬”
“You’re more fascinating than appendix microbiomes. 🦠”
“Your love is more complex than evolutionary biology. 📚”
“You’re my control variable in this experiment of love. 🧪”
“You’re rarer than an appendix function. 🧠”
“If my appendix evolved, it would evolve just to love you. 💕”
“You’re my data set, and love is my conclusion. 📝”
“You’re brighter than any fluorescent microscope. 💡”
“You’re like bacteria—living in my appendix and my heart. 💓”
“You’re the appendix gene no one can delete. 🧬”
“You’ve got me calculating love probabilities all day. 📊”
“You’re more vital than ATP to my energy. ⚡”
“You’re the formula I can’t solve. 📐”
“You’re smarter than Darwin’s theories. 📖”
“You’re my appendix constant—always there. 💫”
“Love may be irrational, but you’re my perfect equation. ➗”

10. Dark Humor Appendix Pick Up Lines 🌑

“Are you my appendix? Because you might kill me, but I can’t let go. 😏”
“You’re the rupture I’d happily endure. 💥”
“If appendix pain is deadly, you’re my sweetest death. ☠️”
“You’re sharper than appendix surgery scars. ✂️”
“I’d bleed for you like an appendix gone wrong. 💉”
“You’re the infection I don’t want cured. 💊”
“You’re deadlier than untreated appendicitis. 🔥”
“You cut deeper than a surgeon. 🩸”
“Even in the morgue, I’d still love you. ⚰️”
“You’re the appendix rupture of my soul. 💔”
“You’re the ER rush that makes my heart race. 🚑”
“Love hurts more than appendix removal, thanks to you. 🖤”
“You’re the complication doctors warn about. 😏”
“You’re my appendix—dangerous, but irresistible. 🔪”
“Even infection can’t spread as fast as my love for you. 💘”
“You’re my post-op scar—painful, but unforgettable. 🩹”
“You inflame my life worse than appendicitis. 🔥”
“You’re worth every hospital bill. 💵”
“You’re my appendix rupture, and I’m not even mad. 🤯”
“If love kills, you’re my executioner. 🪓”
“You’re darker than appendix complications at midnight. 🌌”
“You’re the wound I’d never close. 😈”
“You cut deeper than appendix surgery staples. 🪡”
“Even death couldn’t remove you from my heart. 🖤”
“You’re my appendix pain—tragic, but unforgettable. 💔”

11. Smooth Appendix Rizz Lines 😎

“You’re smoother than an appendix removal scar. ✨”
“Your vibe is sharper than a surgeon’s blade. 😏”
“You’re the appendix mystery I’ll never stop chasing. 🔥”
“Smooth talking is easy, but loving you is smoother. 💘”
“You inflame my appendix with nothing but a look. 👀”
“You’re the scalpel that cuts straight to my heart. 🩺”
“You’re smoother than morphine in my veins. 💊”
“My appendix doesn’t ache when you’re around—it melts. 💞”
“You’re the diagnosis I don’t want cured. 😉”
“You’re smoother than anesthesia in surgery. 🌙”
“Your smile operates smoother than any doctor. 😍”
“You’ve got appendix-level rizz—rare and unforgettable. 💎”
“You’re sharper than appendix pain, smoother than recovery. 💫”
“Smooth moves don’t work on you, but love will. 💕”
“You inflame me, but in the smoothest way. 🔥”
“You’re smoother than stitches closing up. 🪡”
“I’d slide into your heart smoother than an appendix incision. 💘”
“You’re smoother than silk scrubs. 🧵”
“No surgeon’s hand is smoother than your touch. ✋”
“You’re appendix-level smooth—rare and unforgettable. 🌟”
“Smooth talking aside, I just want you. 💖”
“You’re smoother than recovery ice chips. ❄️”
“You’re the appendix rizz no one else can copy. 😎”
“Your love is smooth, steady, and surgical. 🩺”
“I’m not smooth, but you make me feel like I am. 💕”

12. Unique Appendix Pick Up Lines 🌟

“You’re the appendix in my story—rare and unforgettable. 📖”
“You inflame me in ways no one else can. 🔥”
“You’re rarer than appendix surgery without scars. 💎”
“Your love is unique, just like appendix functions. 🧬”
“You’re the one-in-a-million appendix flare that changed my life. 💘”
“You’re unforgettable like post-op hospital food. 🍲”
“You’re rarer than appendix cancer. 🌌”
“No one inflames me the way you do. 😍”
“You’re the appendix pain I’d happily endure. 💕”
“You’re my appendix surprise—completely unexpected. 😏”
“You’re the appendix twist in my love plot. 🎬”
“You make my appendix jealous of your importance. 💫”
“You’re the rare organ my body can’t replace. 🫀”
“You’re unforgettable like emergency surgery. 🚨”
“You’re rarer than appendix rupture survival stories. 🌟”
“You’re the appendix research paper I’ll never finish. 📚”
“You’re the unique ache in my heart. ❤️”
“You’re rarer than appendix evolution theories. 🐒”
“You’re the appendix variable in my life equation. 🧮”
“You’re unforgettable like surgical scars. 🪡”
“You’re my appendix flare-up—one of a kind. 🔥”
“You’re more unique than any MRI scan. 🧠”
“You’re my appendix pain and my appendix cure. 💖”
“You’re my rarest symptom: true love. 💕”
“You’re unforgettable like appendix emergencies. 🚑”

13. Cheeky Appendix Pick Up Lines 😏

“Are you my appendix? Because you’ve got me twisted. 🔥”
“You inflame me in all the right places. 😉”
“You’re hotter than appendix fever and twice as naughty. 💋”
“If you were my appendix, I’d never let you go. 😏”
“You’re sharper than appendix pain at midnight. 🌙”
“I’d risk rupture just to feel your touch. 💘”
“You’re the appendix operation I’d pay to repeat. 💵”
“Your love hurts—but in the best way. 💞”
“You’re hotter than hospital blankets. 🔥”
“You inflame me more than bacteria in my gut. 🤭”
“You’re the appendix complication I want. 💓”
“You’re the ache I’d never treat. 🩺”
“I’d fake appendix pain just to get your attention. 😉”
“You’re the scar I’d love to keep. ✨”
“You’re more dangerous than appendix rupture. 😎”
“You make me sweat harder than fever chills. 🥵”
“You’re the appendix game-changer in my life. 🎮”
“I’d check into your ER any day. 🚑”
“You’re the appendix pain I’d beg for. 💋”

14. Creative Appendix Pick Up Lines 🎨

Are you my appendix? Because I can’t explain the pain, but I can’t let you go. ❤️
If I were your appendix, I’d never want to be removed from your life. ✨
You must be an appendix—small, mysterious, but unforgettable. 💭
They say the appendix has no purpose, but you give mine all the meaning. 💕
Just like an appendix, you’re always on my mind when things get complicated. 🤯
If love had an appendix, it would ache every time you’re away. 💓
I’d rather have you in my life than risk an emergency removal. 🚑
They might call the appendix unnecessary, but you’re absolutely essential. 🌹
Being with you is like my appendix—it feels natural until it’s missing. 💔
I don’t need a doctor to tell me you’re the missing part of me. 🩺
Just like appendicitis, my heart swells whenever you’re around. 😍
You’re like an appendix—everyone underestimates you, but you’re unforgettable. 🌟
I’d never remove you from my side, no matter the pain. 💪
You make my heart race like an appendix about to burst. ⚡
You’re the appendix to my story—unexpected but necessary. 📖
My appendix might be gone, but my love for you is permanent. 💘
You’re my appendix—hidden, mysterious, and always close to my core. 🔥
Just like appendicitis, you make my stomach twist… in love. 🌀
If love surgery was real, I’d keep you in, no matter what. 🛠️
They say the appendix is useless, but I say you’re priceless. 💎
Are you my appendix? Because I can’t stop thinking about losing you. 😢
Love hurts, but you’re the kind of pain I’d never want to cure. 💔➡️❤️
You’re my appendix—hard to explain, but impossible to ignore. 👀
Forget removal—I want you stitched to my heart forever. 🧵❤️
If life is a body, you’re the appendix I never want to lose. 🌍

15. Best Appendix Pick Up Lines 2025-2026 🏆

Are you my appendix? Because I can’t live without you. 💞
Just like appendicitis, you caught me by surprise and changed everything. ⚡
My appendix may be gone, but you’ve filled the empty space in my heart. 💓
If I were a surgeon, I’d stitch you to me forever. 🧑‍⚕️❤️
You’re like an appendix—rare, unique, and unforgettable. 🌹
Appendices may be small, but my love for you is massive. 💘
Are you pain in my side? Because you’re the sweetest ache ever. 😍
My appendix burst, but my heart exploded for you. 💥
Doctors remove appendices, but I’d never let you go. 🫶
You’re the appendix of my heart—hard to explain, but so important. ❤️
Love is like an appendix—it shows up when you least expect it. ✨
If I ever lost you, it’d hurt more than appendicitis. 💔
You’re the best kind of emergency—unexpected love. 🚑💘
Appendices are mysterious, but you’re the mystery I want to solve. 🔍
You make my heart twist like an appendix ready to burst—with love. ❤️🔥
Some things are better removed—but not you. Never you. 🌹
You’re more precious than any organ—especially my appendix. 💎
Appendicitis may bring tears, but you bring smiles. 😊
Are you my appendix? Because I feel complete with you. 💫
Love isn’t in the brain or the heart—it’s in the appendix, where you belong. 🩺
Just like appendicitis, you caught me off guard—and I loved it. ❤️
My appendix scar reminds me that pain passes, but love remains. ✨
You’re the appendix I’ll never let anyone take away. 💪
With you, there’s no surgery—only healing. 💕
You’re the best appendix pick up line I could ever say. 🏆❤️

Conclusion

When it comes to appendix pick up lines, creativity and humor are what make them stand out. Whether you’re looking for something funny, flirty, or witty, these lines can easily break the ice and spark a conversation. Using medical-themed wordplay might sound unusual, but it adds a unique twist that makes you more memorable. Remember, the key to delivering any pick-up line is confidence and timing. So, the next time you want to make someone smile, try dropping one of these appendix-inspired lines—you might just get a laugh, a blush, or even a date!

FAQs

Q1: What are appendix pick up lines?

Appendix pick up lines are playful, witty, and sometimes medically-themed flirty phrases that use the word “appendix” as part of the humor.

Q2: Are appendix pick up lines funny or romantic?

They can be both! Most are funny and quirky, but some can be romantic depending on how you use them.

Q3: Where can I use appendix pick up lines?

You can use them in casual chats, social media captions, dating apps, or just to make someone smile in person.

Q4: Do appendix pick up lines really work?

Yes! While they might sound silly, they often work because they’re unique and unexpected, which grabs attention instantly.

Q5: What’s the best way to deliver an appendix pick up line?

The best way is to say it with confidence and a smile. Humor is attractive, and a lighthearted delivery makes the line more effective.

Dan Brown

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